Activation of Complement by Pityrosporum orbiculare
نویسندگان
چکیده
منابع مشابه
In vitro and in vivo activities of ketoconazole and itraconazole against Pityrosporum orbiculare.
The MICs of ketoconazole and itraconazole against Pityrosporum orbiculare were 0.02 to 0.05 and 0.1 to 0.2 micrograms ml-1, respectively. In a rabbit model, orally administered ketoconazole (1 mg kg-1) afforded protection against experimental pityriasis (tinea) versicolor in all animals. Itraconazole (5 mg kg-1) was effective in four of five rabbits.
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Bioptic specimens from 224 melanocytic naevus lesions and 121 seborrheic keratosis lesions were stained with hematoxylin-eosin and examined under the light microscope. Pityrosporum ovale/orbiculare (Malassezia furfur) was found in 35% of melanocytic naevi and in 36% of seborrheic keratoses. The finding of Pityrosporum ovale/orbiculare was confirmed by PAS (periodic acid shift), methenamide silv...
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A haemolytic assay was used to test the complement fixation ability of 16 serum samples with high concentrations of anti-cardiolipin antibodies. Fourteen patients had clinical complications usually associated with these antibodies--namely, recurrent abortions, thrombosis, or thrombocytopenia. Complement fixation by anticardiolipin antibodies was shown in only four of these patients and was not ...
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Staphylococcal protein A (SpA), acting as a B cell superantigen, binds to the Fab region of human VH3+ Igs. Using SpA abrogated of its IgG Fc binding activity (Mod SpA) as a model B cell superantigen, we determined whether such an interaction causes complement activation. Addition of Mod SpA to human serum led to complement consumption and the generation of C3a. To determine whether this comple...
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C1q is the initiator of the classical complement pathway and, as such, is essential for efficient opsonization and clearance of pathogens, altered self-structures, and apoptotic cells. The ceramide transporter protein (CERT) and its longer splicing isoform CERTL are known to interact with extracellular matrix components, such as type IV collagen, and with the innate immune protein serum amyloid...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1983
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12531644